SpiceCom: A database of phytochemicals in major spices

Ginger

Overview
Compounds
Activities
References
Crop: Ginger
Total No. of activities: 94
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1
Ajayi BO, Adedara IA, Farombi EO(2018). Protective mechanisms of 6-gingerol in dextran sulfate sodium-induced chronic ulcerative colitis in mice. Human & Experimental Toxicology. January. DOI: 10.1177/0960327117751235
  • Antiinflammatory : 6-gingerol
  • Antioxidant : 6-gingerol
  • Antiulcer : 6-gingerol
  • NF-kB-Inhibitor : 6-gingerol
2
Alibakhshi T, Khodayar MJ, Khorsandi L, Rashno M, Zeidooni L(2018). Protective effects of zingerone on oxidative stress and inflammation in cisplatin-induced rat nephrotoxicity. Biomedicine & Pharmacotherapy. 105:225–232. DOI: 10.1016/j.biopha.2018.05.085
  • Nephroprotective : Gingerone
3
Annamalai G, Suresh K(2018). [6]-Shogaol attenuates inflammation, cell proliferation via modulate NF-κB and AP-1 oncogenic signaling in 7,12-dimethylbenz[a]anthracene induced oral carcinogenesis. Biomedicine & Pharmacotherapy. 98:484-490. DOI: 10.1016/j.biopha.2017.12.009
  • Antiinflammatory : 6-shogaol
  • Antitumorigenic : 6-shogaol
  • NF-kB-Inhibitor : 6-shogaol
4
Cui Y, Shi Y, Bao Y, Wang S, Hua Q, Liu Y(2018). Zingerone attenuates diabetic nephropathy through inhibition of nicotinamide adenine dinucleotide phosphate oxidase 4. Biomedicine & Pharmacotherapy. 99:422-430. DOI: 10.1016/j.biopha.2018.01.051
  • Nephroprotective : Gingerone
5
Ezzat SM, Ezzat MI, Okba MM, Menze ET, Abdel-Naim AB(2018). The hidden mechanism beyond ginger (Zingiber officinale Rosc.) potent in vivo and in vitro anti-inflammatory activity. Journal of Ethnopharmacology. 214:113-123. DOI: 10.1016/j.jep.2017.12.019
  • Antiinflammatory : 6-gingerol
  • Antiinflammatory : 6-paradol
  • Antiinflammatory : 6-shogaol
  • Antilipoxygenase : 6-gingerol
  • Antilipoxygenase : 6-shogaol
6
Kim CY, Seo Y, Lee C, Park GH, Jang JH(2018). Neuroprotective Effect and Molecular Mechanism of [6]-Gingerol against Scopolamine-Induced Amnesia in C57BL/6 Mice. Evidence-Based Complementary and Alternative Medicine. 2018:8941564. DOI: 10.1155/2018/8941564
  • Neuroprotective : 6-gingerol
7
Kotowski U, Kadletz L, Schneider S, Foki E, Schmid R, Seemann R3, Thurnher D, Heiduschka G(2018). 6-shogaol induces apoptosis and enhances radiosensitivity in head and neck squamous cell carcinoma cell lines. Phytotherapy research. 32(2):340-347. DOI: 10.1002/ptr.5982
  • Apoptosis inducer : 6-gingerol
  • Apoptosis inducer : 6-shogaol
8
Lee W, Hwang MH, Lee Y, Bae JS(2018). Protective effects of zingerone on lipopolysaccharide-induced hepatic failure through the modulation of inflammatory pathways. Chemico-Biological Interactions. 281:106-110. DOI: 10.1016/j.cbi.2017.12.031
  • Hepatoprotective : Gingerone
9
Luo Y, Chen X, Luo L, Zhang Q, Gao C, Zhuang X, Yuan S, Qiao T(2018). [6]-Gingerol enhances the radiosensitivity of gastric cancer via G2/M phase arrest and apoptosis induction. Oncology Reports. March. DOI: 10.3892/or.2018.6292
  • Apoptosis inducer : 6-gingerol
10
Nedungadi D, Binoy A, Pandurangan N1, Pal S, Nair BG, Mishra N(2018). 6-Shogaol induces caspase-independent paraptosis in cancer cells via proteasomal inhibition. Experimental Cell Research. 364(2):243-251. DOI: 10.1016/j.yexcr.2018.02.018
  • Anticancer : 6-shogaol
  • paraptosis-inducer : 6-shogaol
11
Rehman MU, Rashid SM, Rasool S, Shakeel S, Ahmad B, Ahmad SB, Madkhali H, Ganaie MA, Majid S, Bhat SA(2018). Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy. Archives of Physiology and Biochemistry. :9-Jan. DOI: 10.1080/13813455.2018.1448422
  • antihyperglycemic : Gingerone
  • Antiinflammatory : Gingerone
  • Antioxidant : Gingerone
12
Si W, Chen YP, Zhang J, Chen ZY, Chung HY(2018). Antioxidant activities of ginger extract and its constituents toward lipids. Food Chemistry. 239:1117-1125. DOI: 10.1016/j.foodchem.2017.07.055
  • Antioxidant : 10-gingerol
  • Antioxidant : 6-gingerol
  • Antioxidant : 6-shogaol
  • Antioxidant : 8-gingerol
13
Wang S, Tian M, Yang R, Jing Y, Chen W, Wang J, Zheng X, Wang F(2018). 6-Gingerol Ameliorates Behavioral Changes and Atherosclerotic Lesions in ApoE−/− Mice Exposed to Chronic Mild Stress. Cardiovascular Toxicology. :11-Jan. DOI: 10.1007/s12012-018-9452-4
  • Antiatherosclerotic : 6-gingerol
14
Bernard MM, McConnery JR, Hoskin DW(2017). [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells. Experimental and Molecular Pathology. 102(2):370-376. DOI: 10.1016/j.yexmp.2017.03.006
  • Anti-breast cancer : 10-gingerol
  • Anti-breast cancer : 6-gingerol
  • Anti-breast cancer : 8-gingerol
  • Apoptosis inducer : 10-gingerol
  • Cytotoxic : 10-gingerol
15
Chien-Kei Wei, Yi-Hong Tsai, Michal Korinek, Pei-Hsuan Hung, Mohamed El-Shazly, Yuan-Bin Cheng, Yang-Chang Wu, Tusty-Jiuan Hsieh, Fang-Rong Chang(2017). 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice. International Journl of Molecular Sciences. 18(1). DOI: 10.3390/ijms18010168
  • antihyperglycemic : 6-paradol
  • antihyperglycemic : 6-paradol
  • antihyperglycemic : 6-shogaol
  • Antiobesity : 6-paradol
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