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SpiceCom: A database of phytochemicals in major spices
Ginger
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Compounds
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References
Crop: Ginger
Total No. of activities: 94
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Li TY, Chiang BH(2017). 6-shogaol induces autophagic cell death then triggered apoptosis in colorectal adenocarcinoma HT-29 cells. Biomedicine & Pharmacotherapy. 93:208-217. DOI: 10.1016/j.biopha.2017.06.038
Apoptosis inducer : 6-shogaol
Autophagy inducer : 6-shogaol
17
Lee W, Ku SK, Kim MA, Bae JS(2017). Anti-factor Xa activities of zingerone with anti-platelet aggregation activity. Food and Chemical Toxicology. 105:186-193. DOI: 10.1016/j.fct.2017.04.012
Anticoagulant : Gingerone
Antifactor Xa : Gingerone
Antiplatelet : Gingerone
Antithrombic : Gingerone
18
Sampath C, Rashid MR, Sang S, Ahmedna M(2017). Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway. Food Chemistry. 226:79-88. DOI: 10.1016/j.foodchem.2017.01.056
AntiAGE : 6-gingerol
Antidiabetic : 6-gingerol
antihyperglycemic : 6-gingerol
19
Wang Q, Wei Q, Yang Q, Cao X, Li Q1, Shi F, Tong SS, Feng C, Yu Q, Yu J, Xu X(2017). A novel formulation of [6]-gingerol: Proliposomes with enhanced oral bioavailability and antitumor effect.. International journal of pharmaceutics. 535(2-Jan):308-315. DOI: 10.1016/j.ijpharm.2017.11.006
Antitumor : 6-gingerol
Antitumor : 6-gingerol
20
Hitomi S, Ono K, Terawaki K, Matsumoto C, Mizuno K, Yamaguchi K, Imai R, Omiya Y, Hattori T, Kase Y, Inenaga K(2017). [6]-gingerol and [6]-shogaol, active ingredients of the traditional Japanese medicine hangeshashinto, relief oral ulcerative mucositis-induced pain via action on Na+ channels . Pharmacological Research. 117:288-302. DOI: 10.1016/j.phrs.2016.12.026
Analgesic : 6-gingerol
Analgesic : 6-shogaol
21
Bernard MM, McConnery JR, Hoskin DW(2017). [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells. Experimental and Molecular Pathology. 102(2):370-376. DOI: 10.1016/j.yexmp.2017.03.006
Anti-breast cancer : 10-gingerol
Anti-breast cancer : 6-gingerol
Anti-breast cancer : 8-gingerol
Apoptosis inducer : 10-gingerol
Cytotoxic : 10-gingerol
22
Cuya T, Baptista L, Celmar Costa França T(2017). A molecular dynamics study of components of the ginger (Zingiber officinale) extract inside human acetylcholinesterase: implications for Alzheimer disease.. Journal of biomolecular structure & dynamics. :13-Jan. DOI: 10.1080/07391102.2017.1401004
Antiacetylcholinesterase : Gingerenone-a
23
Seow SLS, Hong SL, Lee GS, Malek SNA, Sabaratnam V(2017). 6-shogaol, a neuroactive compound of ginger (jahe gajah) induced neuritogenic activity via NGF responsive pathways in PC-12 cells.. BMC complementary and alternative medicine. 17(1):334. DOI: 10.1186/s12906-017-1837-6
Neuritogenic : 6-shogaol
24
Samad MB, Mohsin MNAB, Razu BA, Hossain MT, Mahzabeen S, Unnoor N, Muna IA, Akhter F, Kabir AU, Hannan JMA(2017). [6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice. BMC Complementary and Alternative Medicine. 17(1):395. DOI: 10.1186/s12906-017-1903-0
Insulinotropic : 6-gingerol
25
Han Q, Yuan Q, Meng X, Huo J, Bao Y, Xie G(2017). 6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-Y. Oncotarget. 8(26):42001-42006. DOI: 10.18632/oncotarget.16719
Antiinflammatory : 6-shogaol
26
Martin ACBM, Fuzer AM, Becceneri AB, da Silva JA, Tomasin R, Denoyer D, Kim SH, McIntyre KA, Pearson HB, Yeo B, Nagpal A, Ling X, Selistre-de-Araújo HS, Vieira PC, Cominetti MR, Pouliot N(2017). [10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo. Oncotarget. 8(42):72260-72271. DOI: 10.18632/oncotarget.20139
Anticancer : 10-gingerol
Antitumor : 10-gingerol
Apoptosis inducer : 10-gingerol
27
Chien-Kei Wei, Yi-Hong Tsai, Michal Korinek, Pei-Hsuan Hung, Mohamed El-Shazly, Yuan-Bin Cheng, Yang-Chang Wu, Tusty-Jiuan Hsieh, Fang-Rong Chang(2017). 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice. International Journl of Molecular Sciences. 18(1). DOI: 10.3390/ijms18010168
antihyperglycemic : 6-paradol
antihyperglycemic : 6-paradol
antihyperglycemic : 6-shogaol
Antiobesity : 6-paradol
28
Liu CM, Kao CL, Tseng YT, Lo YC, Chen CY(2017). Ginger Phytochemicals Inhibit Cell Growth and Modulate Drug Resistance Factors in Docetaxel Resistant Prostate Cancer Cell. Molecules. 22(9). DOI: 10.3390/molecules22091477
Antiproliferative : 10-gingerol
Antiproliferative : 10-shogaol
Antiproliferative : 6-gingerol
Antiproliferative : 6-shogaol
29
Luettig J, Rosenthal R, Lee IM, Krug SM, Schulzke JD(2016). The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling. Molecular nutrition & food research. 60(12):2576-2586. DOI: 10.1002/mnfr.201600274
Barrier protective : 6-shogaol
NF-kB-Inhibitor : 6-shogaol
TNF-alpha-Inhibitor : 6-shogaol
30
Kathiresan S, Govindhan A(2016). [6]-Shogaol, a Novel Chemopreventor in 7,12-Dimethylbenz[a]anthracene-induced Hamster Buccal Pouch Carcinogenesis. Phytotherapy research. 30(4):646–653. DOI: 10.1002/ptr.5574
Anti-oral cancer : 6-shogaol
Antioxidant : 6-shogaol
Antitumor : 6-shogaol
Apoptosis inducer : 6-shogaol
Chemopreventive : 6-shogaol
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