SpiceCom: A database of phytochemicals in major spices

Black Pepper

Overview
Compounds
Activities
References
Crop: Black Pepper
Total No. of activities: 36
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1
Hwang KS, Kim YK, Park KW, Kim YT.(2017). Piperolein B and piperchabamide D isolated from black pepper (Piper nigrum L.) as larvicidal compounds against the diamondback moth (Plutella xylostella).. Pest management science. 73(8):1564-1567. DOI: 10.1002/ps.4580
  • Insecticide : Piperolein-b
  • Larvicidal : Piperolein-b
2
Sriwiriyajan S, Sukpondma Y, Srisawat T, Madla S, Graidist P.(2017). (-)-Kusunokinin and piperloguminine from Piper nigrum: An alternative option to treat breast cancer.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 92:732-743. DOI: 10.1016/j.biopha.2017.05.130
  • Anticancer : Piperlongumine
3
Vinturelle R,, Mattos C, Meloni J, Nogueira J, Nunes MJ, Vaz IS Jr, Rocha L, Lione V, Castro HC, Chagas EFD(2017). In Vitro Evaluation of Essential Oils Derived from Piper nigrum (Piperaceae) and Citrus limonum (Rutaceae) against the Tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae). Biochemistry Research International. 2017. DOI: 10.1155/2017/5342947
  • Antiinflammatory : Caryophylline
  • Leishmanicidal : Piperine
4
Meriga B, Parim B1, Chunduri VR, Naik RR, Nemani H, Suresh P, Ganapathy S, Sathibabu Uddandrao VV(2017). Antiobesity potential of Piperonal: promising modulation of body composition, lipid profiles and obesogenic marker expression in HFD-induced obese rats . Nutrition & metabolism. 14. DOI: 10.1186/s12986-017-0232-0
  • Antiobesity : Heliotropin
5
Iqbal G, Iqbal A, Mahboob A, Farhat SM, Ahmed T.(2016). Memory Enhancing Effect of Black Pepper in the AlCl3 Induced Neurotoxicity Mouse Model is Mediated Through Its Active Component Chavicine.. Current pharmaceutical biotechnology. 17(11):962-73. DOI: 10.2174/1389201017666160709202124
  • Neurotoxic : Chavicine
6
Michael Samuel, Shüné V. Oliver, Maureen Coetzee and Basil D. Brooke(2016). The larvicidal effects of black pepper (Piper nigrum L.) and piperine against insecticide resistant and susceptible strains of Anopheles malaria vector mosquitoes. Parasites & vectors. 9:238. DOI: 10.1186/s13071-016-1521-6
  • Insecticide : Piperine
7
Yanbei Tu, Yujiao Zhong, Hongjian Du, Wei Luo, Yaya Wen, Qin Li, Chao Zhu, Yanfang Li(2016). Anticholinesterases and antioxidant alkamides from Piper nigrum fruits. Natural Product Research. 30(17):1945-9. DOI: 10.1080/14786419.2015.1089243
  • AChE-Inhibitor : Piperettine
  • AChE-Inhibitor : Piperine
  • BChE-inhibitor : Feruperine
  • BChE-inhibitor : Piperettine
  • BChE-inhibitor : Piperine
8
Yaffe PB, Power Coombs MR, Doucette CD, Walsh M, Hoskin DW(2015). Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress.. Molecular carcinogenesis. 54(10):1070-85. DOI: 10.1002/mc.22176
  • Anti-colon cancer : Piperine
  • Antiproliferative : Piperine
  • Apoptosis inducer : Piperine
9
Pongkorpsakol P, Wongkrasant P, Kumpun S, Chatsudthipong V, Muanprasat C(2015). Inhibition of intestinal chloride secretion by piperine as a cellular basis for the anti-secretory effect of black peppers. Pharmacological Research. 100:271-280. DOI: 10.1016/j.phrs.2015.08.012
  • Antidiarrheal : Piperine
  • Antisecretory : Piperine
10
Paarakh PM, Sreeram DC, D SS, Ganapathy SP (2015). In vitro cytotoxic and in silico activity of piperine isolated from Piper nigrum fruits Linn. . In silico pharmacology. 3(1):9. DOI: 10.1186/s40203-015-0013-2
  • Cytotoxic : Piperine
11
Dutta M, Ghosh AK, Mishra P, Jain G, Rangari V, Chattopadhyay A, Das T, Bhowmick D, Bandyopadhyay D.(2014). Protective effects of piperine against copper-ascorbate induced toxic injury to goat cardiac mitochondria in vitro.. Food & function. 5(9):2252-67. DOI: 10.1039/c4fo00355a
  • Antioxidant : Piperine
12
Tasleem F, Azhar I, Ali SN2, Perveen S, Mahmood ZA(2014). Analgesic and anti-inflammatory activities of Piper nigrum L. Asian Pacific Journal of Tropical Medicine. 7(1):S461-S468. DOI: 10.1016/S1995-7645(14)60275-3
  • Analgesic : Piperine
  • Antiinflammatory : Piperine
13
Minh Truong Do, Hyung Gyun Kim, Jae Ho Choi, Tilak hanal, Bong Hwan Park, Thu PhuongTran, Tae Cheon Jeong, Hye Gwang Jeong(2013). Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells. Food Chemistry. 141(3):2591-2599. DOI: 10.1016/j.foodchem.2013.04.125
  • Antitumor : Piperine
14
Xiaozhou Ying, Xiaowei Chen, Shaowen Chen, Yue Shena, Lei Peng, Hua zi Xu(2013). Piperine inhibits IL-β induced expression of inflammatory mediators in human osteoarthritis chondrocyte. International Immunopharmacology. 17(2):293-299. DOI: 10.1016/j.intimp.2013.06.025
  • Antiinflammatory : Piperine
15
Shrivastava P, Vaibhav K, Tabassum R, Khan A, Ishrat T, Khan MM, Ahmad A, Islam F, Safhi MM, Islam F(2013). Anti-apoptotic and Anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's Rat model. The Journal of Nutritional Biochemistry. 24(4):680-687. DOI: 10.1016/j.jnutbio.2012.03.018
  • Antiapoptotic : Piperine
  • Antiinflammatory : Piperine
  • Neuroprotective : Piperine
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