SpiceCom: A database of phytochemicals in major spices

Black Pepper

Overview
Compounds
Activities
References
Crop: Black Pepper
Total No. of activities: 36
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Per page: 15
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1
Aroonsri Priprem, Pennapa Chonpathompikunlert, Saengrawee Sutthiparinyanont, Jintanaporn Wattanathorn , Jintanaporn Wattanathorn(2011). Antidepressant and cognitive activities of intranasal piperine-encapsulated liposomes. Advances in Bioscience and Biotechnology. 2:108-116 . DOI: 10.4236/abb.2011.22017
  • Antidepressant : Piperine
2
B.-S.Park, D.-J.Son, Y.-H.Park, T.W.Kim, S.-E.Lee(2007). Antiplatelet effects of acidamides isolated from the fruits of Piper longum L.. Phytomedicine. 14(12):853-855. DOI: 10.1016/j.phymed.2007.06.011
  • Antiplatelet : Piperlongumine
3
Bang JS, Oh DH, Choi HM, Sur BJ, Lim SJ, Kim JY, Yang HI, Yoo MC, Hahm DH, Kim KS.(2009). Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models. Arthritis research & therapy. 11(2):R49. DOI: 10.1186/ar2662
  • Antiarthritic : Piperine
  • Antiinflammatory : Piperine
  • Antinociceptive : Piperine
4
Bukhari IA, Pivac N, Alhumayyd MS, Mahesar AL, Gilani AH(2013). The analgesic and anticonvulsant effects of piperine in mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 64(6):789-94. DOI: NoDOI2
  • Analgesic : Piperine
  • Anticonvulsant : Piperine
5
Dogra RK, Khanna S, Shanker R(2004). Immunotoxicological effects of piperine in mice. Toxicology. 196(3):229-236. DOI: 10.1016/j.tox.2003.10.006
  • Immunosuppressant : Piperine
  • immunotoxic : Piperine
6
Dutta M, Ghosh AK, Mishra P, Jain G, Rangari V, Chattopadhyay A, Das T, Bhowmick D, Bandyopadhyay D.(2014). Protective effects of piperine against copper-ascorbate induced toxic injury to goat cardiac mitochondria in vitro.. Food & function. 5(9):2252-67. DOI: 10.1039/c4fo00355a
  • Antioxidant : Piperine
7
E.S Sunila, G Kuttan(2004). Immunomodulatory and antitumor activity of Piper longum Linn. and piperine. Journal of Ethnopharmacology. 90(2-3):Journal of Ethnophar. DOI: 10.1016/j.jep.2003.10.016
  • Antitumor : Piperine
  • Immunomodulator : Piperine
8
Ee GC, Lim CM, Rahmani M, Shaari K, Bong CF(2010). Pellitorine, a potential anti-cancer lead compound against HL6 and MCT-7 cell lines and microbial transformation of piperine from Piper Nigrum. Molecules. 15(4):2398-404. DOI: 10.3390/molecules15042398
  • Cytotoxic : Pellitorine
9
Evan Prince Sabina, Annie Deborah Harris Souriyan, Deborah Jackline, Mahaboob Khan Rasool(2010). Piperine, an active ingredient of black pepper attenuates acetaminophen-induced hepatotoxicity in mice. Asian Pacific Journal of Tropical Medicine. 3(12):971-976. DOI: 10.1016/S1995-7645(11)60011-4
  • Hepatoprotective : Piperine
10
Ferreira C., Soares D. C., Barreto-Junior C. B., et al.(2011). Leishmanicidal effects of piperine, its derivatives, and analogues on Leishmania amazonensis. Phytochemistry. Phytochemistry. 72(17):2155-2164. DOI: 10.1016/j.phytochem.2011.08.006
  • Leishmanicidal : Piperine
11
Hirata N, Tokunaga M, Naruto S, Iinuma M, Matsuda H(2007). Testosterone 5alpha-reductase inhibitory active constituents of Piper nigrum leaf. Biological & pharmaceutical bulletin. 30(12):2402-5. DOI: 10.1248/bpb.30.2402
  • 5-Alpha-Reductase-Inhibitor : (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin
  • 5-Alpha-Reductase-Inhibitor : (-)-cubebin
  • 5-Alpha-Reductase-Inhibitor : Piperine
  • Melanogenic : (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin
12
Hwang KS, Kim YK, Park KW, Kim YT.(2017). Piperolein B and piperchabamide D isolated from black pepper (Piper nigrum L.) as larvicidal compounds against the diamondback moth (Plutella xylostella).. Pest management science. 73(8):1564-1567. DOI: 10.1002/ps.4580
  • Insecticide : Piperolein-b
  • Larvicidal : Piperolein-b
13
Iqbal G, Iqbal A, Mahboob A, Farhat SM, Ahmed T.(2016). Memory Enhancing Effect of Black Pepper in the AlCl3 Induced Neurotoxicity Mouse Model is Mediated Through Its Active Component Chavicine.. Current pharmaceutical biotechnology. 17(11):962-73. DOI: 10.2174/1389201017666160709202124
  • Neurotoxic : Chavicine
14
Lai LH, Fu QH, Liu Y, Jiang K, Guo QM, Chen QY, Yan B, Wang QQ, Shen JG.(2012). Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model.. Acta pharmacologica Sinica. 33(4):523-30. DOI: 10.1038/aps.2011.209
  • Antitumor : Piperine
  • Antitumor : Piperine
15
Li S, Wang C, Li W, Koike K, Nikaido T, Wang MW.(2007). Antidepressant-like effects of piperine and its derivative, antiepilepsirine. Journal of Asian natural products research. 9(3-5):421-30. DOI: 10.1080/10286020500384302
  • Antidepressant : Piperine
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