SpiceCom: A database of phytochemicals in major spices

Cinnamon

Overview
Compounds
Activities
References
Crop: Cinnamon
Total No. of activities: 46
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1
Yoo W, Yoo D, Hong E, Jung E, Go Y, Singh SVB, Khang G, Lee D3(2018). Acid-activatable oxidative stress-inducing polysaccharide nanoparticles for anticancer therapy.. Journal of controlled release : official journal of the Controlled Release Society. 269:235-244. DOI: 10.1016/j.jconrel.2017.11.023
  • Anticancer : Cinnamaldehyde
2
Yue Wang, Yi Zhang, Yan-qin Shi, Xian-hua Pan, Yan-hua Lu, Ping Cao(2018). Antibacterial effects of cinnamon (Cinnamomum zeylanicum) bark essential oil on Porphyromonas gingivalis. Microbial Pathogenesis. 116:26-32. DOI: 10.1016/j.micpath.2018.01.009
  • Antibacterial : Cinnamaldehyde
  • Antibiofilm : Cinnamaldehyde
  • Antimicrobial : Cinnamaldehyde
3
Hosni AA, Abdel-Moneim AA, Abdel-Reheim ES, Mohamed SM, Helmy H(2017). Cinnamaldehyde potentially attenuates gestational hyperglycemia in rats through modulation of PPARγ, proinflammatory cytokines and oxidative stress.. Biomedicine & Pharmacotherapy. 88:52-60. DOI: 10.1016/j.biopha.2017.01.054
  • Hypoglycemic : Cinnamaldehyde
4
Monteiro IN, Monteiro ODS, Costa-Junior LM, da Silva Lima A, Andrade EHA, Maia JGS, Mouchrek Filho VE.(2017). Chemical composition and acaricide activity of an essential oil from a rare chemotype of Cinnamomum verum Presl on Rhipicephalus microplus (Acari: Ixodidae).. Vet Parasitol.. 238:00:00(-):54-57. DOI: 10.1016/j.vetpar.2017.03.016
  • Acaricide : Benzyl-benzoate
  • Acaricide : Eugenol
5
Sharma UK, Sharma AK, Gupta A, Kumar R, Pandey A, Pandey AK(2017). Pharmacological activities of cinnamaldehyde and eugenol: antioxidant, cytotoxic and anti-leishmanial studies.. Cellular and molecular biology (Noisy-le-Grand, France). 63(6):73-78. DOI: 10.14715/cmb/2017.63.6.15
  • Antileishmanial : Cinnamaldehyde
  • Antileishmanial : Eugenol
  • Antioxidant : Cinnamaldehyde
  • Antioxidant : Eugenol
  • Cytotoxic : Cinnamaldehyde
  • Cytotoxic : Eugenol
6
Deletre E, Chandre F, Barkman B, Menut C, Martin T(2016). Naturally occurring bioactive compounds from four repellent essential oils against Bemisia tabaci whiteflies. Pest management science. 72(1):179-89. DOI: 10.1002/ps.3987
  • Repellent : Cinnamaldehyde
7
Wong HY, Tsai KD1, Liu YH, Yang SM1,, Chen TW, Cherng J, Chou KS, Chang CM, Yao BT, Cherng JM(2016). Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo. Phytotherapy research : PTR. 30(2):331-40. DOI: 10.1002/ptr.5536
  • Anticancer : 2-methoxycinnamaldehyde
  • Antiproliferative : 2-methoxycinnamaldehyde
  • Chemopreventive : 2-methoxycinnamaldehyde
  • NF-kB-Inhibitor : 2-methoxycinnamaldehyde
  • Topoisomerase-I-Inhibitor : 2-methoxycinnamaldehyde
  • Topoisomerase-II-Inhibitor : 2-methoxycinnamaldehyde
8
Mendes SJ, Sousa FI, Pereira DM, Ferro TA, Pereira IC, Silva BL, Pinheiro AJ, Mouchrek AQ, Monteiro-Neto V, Costa SK, Nascimento JL, Grisotto MA, da Costa R, Fernandes ES(2016). Cinnamaldehyde modulates LPS-induced systemic inflammatory response syndrome through TRPA1-dependent and independent mechanisms. International Immunopharmacology. 34:60-70. DOI: 10.1016/j.intimp.2016.02.012
  • Immunomodulatory : Cinnamaldehyde
9
AkshayJawalea, Ashok Kumar Datusaliaa, Mahendra Bishnoi, Shyam S.Sharma(2016). Reversal of diabetes-induced behavioral and neurochemical deficits by cinnamaldehyde. Phytomedicine. 23(9):923-930. DOI: 10.1016/j.phymed.2016.04.008
  • AChE-Inhibitor : Cinnamaldehyde
10
Imad Hadi Hameed, Huda Jasim Altameme, Ghaidaa Jihadi Mohammed(2016). Evaluation of Antifungal and Antibacterial Activity and Analysis of Bioactive Phytochemical Compounds of Cinnamomum Zeylanicum (Cinnamon Bark) using Gas Chromatography-Mass Spectrometry. Oriental Journal of Chemistry. 32(4):1769-1788. DOI: 10.13005/ojc/320406
  • Antimicrobial : Cinnamaldehyde
11
Connell BJ, Chang SY, Prakash E, Yousfi R, Mohan V, Posch W, Wilflingseder D, Moog C, Kodama EN7, Clayette P, Lortat-Jacob H(2016). A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 Upregulation.. PloS one. 11(10). DOI: 10.1371/journal.pone.0165386
  • AntiHIV : Ind02-trimer
12
Perng DS, Tsai YH, Cherng J, Wang JS, Chou KS, Shih CW, Cherng JM(2016). Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde. Drug Design, Development and Therapy. 10:141–153. DOI: 10.2147/DDDT.S93599
  • Anticancer : 2-methoxycinnamaldehyde
  • NF-kB-Inhibitor : 2-methoxycinnamaldehyde
  • Topoisomerase-I-Inhibitor : 2-methoxycinnamaldehyde
  • Topoisomerase-II-Inhibitor : 2-methoxycinnamaldehyde
13
Kuen-daw Tsai, Yi-Heng Liu, Ta-Wei Chen, Shu-Mei Yang, Ho-Yiu Wong, Jonathan Cherng, Kuo-Shen Chou, Jaw-Ming Cherng(2016). Cuminaldehyde from Cinnamomum verum Induces Cell Death through Targeting Topoisomerase 1 and 2 in Human Colorectal Adenocarcinoma COLO 205 Cells. Nutrients. 8(6). DOI: 10.3390/nu8060318
  • Anticancer : Cuminaldehyde
  • Antiproliferative : Cuminaldehyde
  • Chemopreventive : Cuminaldehyde
14
Hagenlocher Y, Kiessling K, Schäffer M, Bischoff SC, Lorentz A(2015). Cinnamaldehyde is the main mediator of cinnamon extract in mast cell inhibition.. European journal of nutrition. 54(8):1297-309. DOI: 10.1007/s00394-014-0810-0
  • Antiallergic : Cinnamaldehyde
15
Yong-Guy Kim, Jin-Hyung Lee, Soon-Il Kim, Kwang-Hyun Baek, Jintae Lee(2015). Cinnamon bark oil and its components inhibit biofilm formation and toxin production. International Journal of Food Microbiology. 195:30-39. DOI: 10.1016/j.ijfoodmicro.2014.11.028
  • Antibiofilm : Cinnamaldehyde
  • Antibiofilm : Eugenol
  • Antihemolytic : Cinnamaldehyde
  • Antihemolytic : Eugenol
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