SpiceCom: A database of phytochemicals in major spices

Turmeric

Overview
Compounds
Activities
References
Crop: Turmeric
Total No. of activities: 67
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1
A.J. Ruby, G. Kuttan, K. Dinesh Babu, K.N. Rajasekharan, R. Kuttan(1995). Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Letters. 94(1): 79-83. DOI: 10.1016/0304-3835(95)03827-J
  • Antioxidant : Curcumin
  • Antitumor : Curcumin
2
Abbaoui A, Chatoui H, El Hiba O, Gamrani H(2017). Neuroprotective effect of curcumin-I in copper-induced dopaminergic neurotoxicity in rats: A possible link with Parkinson’s disease. Neuroscience Letters. 660:103-108. DOI: 10.1016/j.neulet.2017.09.032
  • Neuroprotective : Curcumin
3
Akinyemi AJ, Oboh G, Fadaka AO, Olatunji BP, Akomolafe S(2017). Curcumin administration suppress acetylcholinesterase gene expression in cadmium treated rats. NeuroToxicology. 62:75-79. DOI: 10.1016/j.neuro.2017.05.004
  • Antiacetylcholinesterase : Curcumin
4
Akinyemi AJ, Oboh G, Ogunsuyi O, Abolaji AO, Udofia A(2018). Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model. Metabolic Brain Disease. 33(2):369-375. DOI: 10.1007/s11011-017-0100-7
  • Antiacetylcholinesterase : Curcumin
  • Antiaging : Curcumin
5
Akinyemi AJ, Oboh G, Oyeleye SI, Ogunsuyi O(2017). Anti-amnestic Effect of Curcumin in Combination with Donepezil, an Anticholinesterase Drug: Involvement of Cholinergic System. Neurotoxicity Research. 31(4):560-569. DOI: 10.1007/s12640-017-9701-5
  • Anti-amnestic : Curcumin
6
Alaikov T, Konstantinov SM, Tzanova T, Dinev K, Topashka-Ancheva M, Berger MR.(2007). Antineoplastic and anticlastogenic properties of curcumin.. Annals of the New York Academy of Sciences. 1095:355-70. DOI: 10.1196/annals.1397.039
  • Anticlastogen : Curcumin
7
Ali AH, Sudi S, Basir R, Embi N, Sidek HM(2017). The Antimalarial Effect of Curcumin Is Mediated by the Inhibition of Glycogen Synthase Kinase-3β. Journal of Medicinal Food. 20(2):152-161. DOI: 10.1089/jmf.2016.3813
  • Antimalarial : Curcumin
8
Alves TF, Chaud MV, Grotto D, Jozala AF, Pandit R, Rai M, Dos Santos CA(2018). Association of Silver Nanoparticles and Curcumin Solid Dispersion: Antimicrobial and Antioxidant Properties. AAPS PharmSciTech. 19(1):225-231. DOI: 10.1208/s12249-017-0832-z
  • Antimicrobial : Curcumin
  • Antioxidant : Curcumin
9
Anoop K.SinghGurmel S.SidhuT.DeepaRadha K.Maheshwari(1996). Curcumin inhibits the proliferation and cell cycle progression of human umbilical vein endothelial cell. Cancer Letters. 107(1):109-115. DOI: 10.1016/0304-3835(96)04357-1
  • Anticancer : Curcumin
10
Araújo LA, Araújo RG, Gomes FO, Lemes SR, Almeida LM, Maia LJ, Gonçalves PJ, Mrué F, Silva-Junior NJ, Melo-Reis PR(2016). Physicochemical/photophysical characterization and angiogenic properties of Curcuma longa essential oil. Anais da Academia Brasileira de Ciencias. 88(3):1889-1897. DOI: 10.1590/0001-3765201620150600
  • Angiogenic : Curcumin
11
Babu PS, Srinivasan K.(1997). Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats.. Molecular and cellular biochemistry. 166(2-Jan):169-75. DOI: 10.1023/A:1006819605211
  • Hypolipidemic : Curcumin
12
Benammi H, El Hiba O, Romane A, Gamrani H.(2014). A blunted anxiolytic like effect of curcumin against acute lead induced anxiety in rat: involvement of serotonin.. Acta histochemica. 116(5):920-5. DOI: 10.1016/j.acthis.2014.03.002
  • Anxiolytic : Curcumin
13
Bharal N, Sahaya K, Jain S, Mediratta PK, Sharma KK(2008). Curcumin has Anticonvulsant Activity onIncreasing Current Electroshock Seizuresin Mice. Phytotherapy research. 22(12):1660-1664. DOI: 10.1002/ptr.2551
  • Anticonvulsant : Curcumin
  • Anxiogenic : Curcumin
14
Busari ZA, Dauda KA1, Morenikeji OA, Afolayan F, Oyeyemi OT, Meena J, Sahu D, Panda AK(2017). Antiplasmodial Activity and Toxicological Assessment of Curcumin PLGA-Encapsulated Nanoparticles. Frontiers in Pharmacology. 8:622. DOI: 10.3389/fphar.2017.00622
  • Antimalarial : Curcumin
  • Antiplasmodial : Curcumin
15
Cai‐Jun Xie, Ai‐Ping Gu, Jun Cai, Yi Wu, and Rui‐Cong Chen(2018). Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke. Brain and Behaviour. 8(2). DOI: 10.1002/brb3.921
  • Anti-apoptotic : Curcumin
  • Neuroprotective : Curcumin
16
Ceremuga TE, Helmrick K, Kufahl Z, Kelley J, Keller B, Philippe F, Golder J, Padrón G.(2017). Investigation of the Anxiolytic and Antidepressant Effects of Curcumin, a Compound From Turmeric (Curcuma longa), in the Adult Male Sprague-Dawley Rat.. Holistic nursing practice. 31(3):193-203. DOI: 10.1097/HNP.0000000000000208
  • Antidepressant : Curcumin
  • Anxiolytic : Curcumin
17
Chang M, Wu M, Li H(2017). Curcumin combined with glycyrrhetinic acid inhibits the development of hepatocellular carcinoma cells by down-regulating the PTEN/PI3K/AKT signalling pathway. American Journal of Translational Research. 9(12):5567–5575. DOI: NoDOI3
  • Anti-hepatocellular carcinoma : Curcumin
18
Chen C, Jin S, Xiang X, Wang X, Shi Q, Yang M, Ji S, Huang R, Song C(2017). Enrichment and Cytotoxic Activity of Curcuminoids from Turmeric Using Macroporous Resins. Journal of Food Science. 82(9):2024-2030. DOI: 10.1111/1750-3841.13800
  • Cytotoxic : Bisdemethoxycurcumin
  • Cytotoxic : Curcumin
  • Cytotoxic : Demethoxycurcumin
19
Chen C, Long L, Zhang F, Chen Q, Chen C, Yu X, Liu Q, Bao J, Long Z(2018). Antifungal activity, main active components and mechanism of Curcuma longa extract against Fusarium graminearum. PLoS One. 13(3). DOI: 10.1371/journal.pone.0194284
  • Antifungal : Beta-elemene
  • Antifungal : Curcumenol
  • Antifungal : Curcumin
  • Antifungal : Curcumol
  • Antifungal : Curdione
  • Antifungal : Curzerene
  • Antifungal : Germacrone
  • Antifungal : Isocurcumenol
20
Chen G, Li J, Cai Y, Zhan J, Gao J, Song M, Shi Y, Yang Z(2017). A Glycyrrhetinic Acid-Modified Curcumin Supramolecular Hydrogel for liver tumor targeting therapy. Scientific Reports. 7:44210. DOI: 10.1038/srep44210
  • Anti-hepatocellular carcinoma : Curcumin
21
Chen M, Chang YY, Huang S, Xiao LH, Zhou W, Zhang LY, Li C, Zhou RP, Tang J, Lin L, Du ZY, Zhang K(2017). Aromatic‐Turmerone Attenuates LPS‐Induced Neuroinflammation and Consequent Memory Impairment by Targeting TLR4‐Dependent Signaling Pathway. Molecular Nutrition & Food Research. 62(2). DOI: 10.1002/mnfr.201700281
  • Anti-neuroinflammatory : Ar-turmerone
22
Cheng T, Zhao Y, Li B, Cheng M, Wang J, Zhang X(2017). Curcumin Attenuation of Wear Particle-Induced Osteolysis via RANKL Signaling Pathway Suppression in Mouse Calvarial Model. Mediators of Inflammation. 2017:5784374. DOI: 10.1155/2017/5784374
  • Anti-osteolysis : Curcumin
23
Choi GY, Kim HB, Hwang ES, Lee S, Kim MJ, Choi JY, Lee SO, Kim SS, Park JH(2017). Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats. Mediators of Inflammation. 2017:6280925. DOI: 10.1155/2017/6280925
  • Antidepressant : Curcumin
  • Antiinflammatory : Curcumin
  • Neuroprotective : Curcumin
24
Curic S, Wu Y, Shan B, Schaaf C, Utpadel D, Lange M, Kuhlen D, Perone MJ, Arzt E, Stalla GK, Renner U.(2013). Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas.. Journal of neuro-oncology. 113(3):385-96. DOI: 10.1007/s11060-013-1148-9
  • Antitumorigenic : Curcumin
25
Dai P, Mao Y, Sun X, Li X, Muhammad I, Gu W, Zhang D, Zhou Y, Ni Z, Ma J, Huang S(2017). Attenuation of Oxidative Stress-Induced Osteoblast Apoptosis by Curcumin is Associated with Preservation of Mitochondrial Functions and Increased Akt-GSK3β Signaling. Cellular Physiology and Biochemistry. 41(2):661-677. DOI: 10.1159/000457945
  • Antiapoptotic : Curcumin
  • Antiosteoporotic : Curcumin
  • Cytoprotective : Curcumin
26
Darbinyan LV, Hambardzumyan LE, Simonyan KV, Chavushyan VA, Manukyan LP, Badalyan SA, Khalaji N, Sarkisian VH(2017). Protective effects of curcumin against rotenone-induced rat model of Parkinson’s disease: in vivo electrophysiological and behavioral study. Metabolic Brain Disease. 32(6):1791–1803. DOI: 10.1007/s11011-017-0060-y
  • Neuroprotective : Curcumin
27
Du ZY1, Bao YD, Liu Z, Qiao W, Ma L, Huang ZS, Gu LQ, Chan AS(2006). Curcumin analogs as potent aldose reductase inhibitors. Archiv der Pharmazie. 339(3):123-8. DOI: 10.1002/ardp.200500205
  • Aldose-Reductase-Inhibitor : Curcumin
28
Enomoto A, Yamada J, Morita A, Miyagawa K(2017). Bisdemethoxycurcumin enhances X-ray-induced apoptosis possibly through p53/Bcl-2 pathway. Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 815:1-5. DOI: 10.1016/j.mrgentox.2016.12.005
  • Apoptosis inducer : Bisdemethoxycurcumin
29
Fan Y, Chen H, Peng H, Huang F, Zhong J, Zhou J(2017). Molecular Mechanisms of Curcumin Renoprotection in Experimental Acute Renal Injury. Frontiers in pharmacology. 8:912. DOI: 10.3389/fphar.2017.00912
  • Nephroprotective : Curcumin
30
Frank A, Abu-Lafi S, Adawi A, Schwed JS, Stark H, Rayan A(2017). From medicinal plant extracts to defined chemical compounds targeting the histamine H4 receptor: Curcuma longa in the treatment of inflammation.. Inflammation research :. 66(10):923-929. DOI: 10.1007/s00011-017-1075-x
  • Antiinflammatory : Bisdemethoxycurcumin
  • Antiinflammatory : Bisdemethoxycurcumin
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