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SpiceCom: A database of phytochemicals in major spices
Turmeric
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Crop: Turmeric
Total No. of activities: 67
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1
Chen C, Long L, Zhang F, Chen Q, Chen C, Yu X, Liu Q, Bao J, Long Z(2018). Antifungal activity, main active components and mechanism of Curcuma longa extract against Fusarium graminearum. PLoS One. 13(3). DOI: 10.1371/journal.pone.0194284
Antifungal : Beta-elemene
Antifungal : Curcumenol
Antifungal : Curcumin
Antifungal : Curcumol
Antifungal : Curdione
Antifungal : Curzerene
Antifungal : Germacrone
Antifungal : Isocurcumenol
2
Zhao W, Zhou X, Qi G, Guo Y(2018). Curcumin suppressed the prostate cancer by inhibiting JNK pathways via epigenetic regulation. Journal of Biochemical and Molecular Toxicology. 32(5). DOI: 10.1002/jbt.22049
Anti-prostate cancer : Curcumin
3
Perna A, De Luca A, Adelfi L, Pasquale T, Varriale B, Esposito T(2018). Effects of different extracts of curcumin on TPC1 papillary thyroid cancer cell line. BMC Complementary and Alternative Medicine. 18(1):63. DOI: 10.1186/s12906-018-2125-9
Antiinflammatory : Curcumin
Antioxidant : Curcumin
Antiproliferative : Curcumin
4
Galli GM, Da Silva AS, Biazus AH, Reis JH, Boiago MM, Topazio JP, Migliorini MJ, Guarda NS, Moresco RN, Ourique AF, Santos CG, Lopes LS, Baldissera MD, Stefani LM(2018). Feed addition of curcumin to laying hens showed anticoccidial effect, and improved egg quality and animal health. Research in Veterinary Science. 118:101-106. DOI: 10.1016/j.rvsc.2018.01.022
Anticoccidial : Curcumin
5
Cai‐Jun Xie, Ai‐Ping Gu, Jun Cai, Yi Wu, and Rui‐Cong Chen(2018). Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke. Brain and Behaviour. 8(2). DOI: 10.1002/brb3.921
Anti-apoptotic : Curcumin
Neuroprotective : Curcumin
6
Huang HI, Chio CC, Lin JY(2018). Inhibition of EV71 by curcumin in intestinal epithelial cells. PloS one. 13(1). DOI: 10.1371/journal.pone.0191617
Anti-EV71 : Curcumin
Antiviral : Curcumin
7
Kukula-Koch W, Grabarska A, Łuszczki J, Czernicka L, Nowosadzka E, Gumbarewicz E, Jarząb A, Audo G, Upadhyay S, Głowniak K, Stepulak A(2018). Superior anticancer activity is demonstrated by total extract of Curcuma longa L. as opposed to individual curcuminoids separated by centrifugal partition chromatography. Phytotherapy Research. 32(5):933-942. DOI: 10.1002/ptr.6035
Anti-lung cancer : Bisdemethoxycurcumin
Anti-lung cancer : Demethoxycurcumin
Antiproliferative : Bisdemethoxycurcumin
Antiproliferative : Demethoxycurcumin
8
Huang L, Chen C, Zhang X, Li X, Chen Z, Yang C, Liang X, Zhu G, Xu Z(2018). Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation. Journal of Molecular Neuroscience : MN. 64(1):129-139. DOI: 10.1007/s12031-017-1006-x
Neuroprotective : Curcumin
9
Marini E, Di Giulio M, Magi G, Di Lodovico S, Cimarelli ME, Brenciani A, Nostro A, Cellini L, Facinelli B(2018). Curcumin, an antibiotic resistance breaker against a multiresistant clinical isolate of Mycobacterium abscessus. Phytotherapy Research. 32(3):488-495. DOI: 10.1002/ptr.5994
Antibiofilm : Curcumin
10
Jin M, Park SY, Shen Q, Lai Y, Ou X, Mao Z, Lin D, Yu Y, Zhang W(2018). Anti-neuroinflammatory effect of curcumin on Pam3CSK4-stimulated microglial cells. International Journal of Molecular Medicine. 41(1):521-530. DOI: 10.3892/ijmm.2017.3217
Anti-neuroinflammatory : Curcumin
11
Zhao Q, Guan J, Qin Y, Ren P, Zhang Z, Lv J, Sun S, Zhang C, Mao W(2018). Curcumin sensitizes lymphoma cells to DNA damage agents through regulating Rad51-dependent homologous recombination. Biomedicine & Pharmacotherapy. 97:115-119. DOI: 10.1016/j.biopha.2017.09.078
Antitumor : Curcumin
12
Jain A, Rani V(2018). Mode of treatment governs curcumin response on doxorubicin-induced toxicity in cardiomyoblasts. Molecular and Cellular Biochemistry. 442(1-2):81-96. DOI: 10.1007/s11010-017-3195-6
Cardioprotective : Curcumin
13
Akinyemi AJ, Oboh G, Ogunsuyi O, Abolaji AO, Udofia A(2018). Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model. Metabolic Brain Disease. 33(2):369-375. DOI: 10.1007/s11011-017-0100-7
Antiacetylcholinesterase : Curcumin
Antiaging : Curcumin
14
Wang J, Li XM, Bai Z, Chi BX, Wei Y, Chen X(2018). Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway. Journal of Ethnopharmacology. 210:1-9. DOI: 10.1016/j.jep.2017.06.037
Anti-colon cancer : Curcumol
Antiproliferative : Curcumol
15
Zhu X, Zhu R(2018). Curcumin suppresses the progression of laryngeal squamous cell carcinoma through the upregulation of miR-145 and inhibition of the PI3K/Akt/mTOR pathway. OncoTargets and Therapy. 11:3521-3531. DOI: 10.2147/OTT.S159236
Anti-laryngeal cancer : Curcumin
Antiproliferative : Curcumin
16
Lee YH, Song NY, Suh J, Kim DH, Kim W, Ann J, Lee J, Baek JH, Na HK, Surh YJ(2018). Curcumin suppresses oncogenicity of human colon cancer cells by covalently modifying the cysteine 67 residue of SIRT1. Cancer Letters. 431:219-229. DOI: 10.1016/j.canlet.2018.05.036
Anti-colon cancer : Curcumin
17
Alves TF, Chaud MV, Grotto D, Jozala AF, Pandit R, Rai M, Dos Santos CA(2018). Association of Silver Nanoparticles and Curcumin Solid Dispersion: Antimicrobial and Antioxidant Properties. AAPS PharmSciTech. 19(1):225-231. DOI: 10.1208/s12249-017-0832-z
Antimicrobial : Curcumin
Antioxidant : Curcumin
18
Li X, Ma S, Yang P, Sun B, Zhang Y, Sun Y, Hao M, Mou R, Jia Y(2018). Anticancer effects of curcumin on nude mice bearing lung cancer A549 cell subsets SP and NSP cells.. Oncology letters. 16(5):6756-6762. DOI: 10.3892/ol.2018.9488
Anti-lung cancer : Curcumin
19
Garrido-Armas M, Corona JC, Escobar ML, Torres L, Ordóñez-Romero F, Hernández-Hernández A, Arenas-Huertero F(2018). Paraptosis in human glioblastoma cell line induced by curcumin. Toxicology in Vitro. 51:63-73. DOI: 10.1016/j.tiv.2018.04.014
paraptosis-inducer : Curcumin
20
Shakeri A, Ward N, Panahi Y, Sahebkar A.(2018). Anti-angiogenic activity of curcumin in cancer therapy: a narrative review.. Current vascular pharmacology. 16. DOI: 10.2174/1570161116666180209113014
Angiogenic : Curcumin
21
Fan Y, Chen H, Peng H, Huang F, Zhong J, Zhou J(2017). Molecular Mechanisms of Curcumin Renoprotection in Experimental Acute Renal Injury. Frontiers in pharmacology. 8:912. DOI: 10.3389/fphar.2017.00912
Nephroprotective : Curcumin
22
Chang M, Wu M, Li H(2017). Curcumin combined with glycyrrhetinic acid inhibits the development of hepatocellular carcinoma cells by down-regulating the PTEN/PI3K/AKT signalling pathway. American Journal of Translational Research. 9(12):5567–5575. DOI: NoDOI3
Anti-hepatocellular carcinoma : Curcumin
23
Pan Y, Zhao D, Yu N, An T, Miao J, Mo F, Gu Y, Zhang D, Gao S, Jiang G(2017). Curcumin improves glycolipid metabolism through regulating peroxisome proliferator activated receptor γ signalling pathway in high-fat diet-induced obese mice and 3T3-L1 adipocytes. Royal Society open science. 4(11):170917. DOI: 10.1098/rsos.170917
Antiobesity : Curcumin
24
Yan FS, Sun JL, Xie WH, Shen L, Ji HF(2017). Neuroprotective Effects and Mechanisms of Curcumin-Cu(II) and -Zn(II) Complexes Systems and Their Pharmacological Implications. Nutrients. 10(1). DOI: 10.3390/nu10010028
Antialzheimer's : Curcumin
Neuroprotective : Curcumin
25
Mou S, Zhou Z, He Y, Liu F, Gong L(2017). Curcumin inhibits cell proliferation and promotes apoptosis of laryngeal cancer cells through Bcl-2 and PI3K/Akt, and by upregulating miR-15a. Oncology Letters. 14(4):4937-4942. DOI: 10.3892/ol.2017.6739
Anti-laryngeal cancer : Curcumin
Antiproliferative : Curcumin
Apoptosis inducer : Curcumin
26
Cheng T, Zhao Y, Li B, Cheng M, Wang J, Zhang X(2017). Curcumin Attenuation of Wear Particle-Induced Osteolysis via RANKL Signaling Pathway Suppression in Mouse Calvarial Model. Mediators of Inflammation. 2017:5784374. DOI: 10.1155/2017/5784374
Anti-osteolysis : Curcumin
27
Zang S, Tang Q, Dong F, Liu H, Li L, Guo F, Pan X, Lin H, Zeng W, Cai Z, Zhong Q, Zang N, Zang L(2017). Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1. Oncology Reports. 38(6):3583-3591. DOI: 10.3892/or.2017.6028
Antitumor : Curcumol
Apoptosis inducer : Curcumol
28
Zhou QM, Sun Y, Lu YY, Zhang H, Chen QL, Su SB(2017). Curcumin reduces mitomycin C resistance in breast cancer stem cells by regulating Bcl-2 family-mediated apoptosis. Cancer Cell International. 17:84. DOI: 10.1186/s12935-017-0453-3
Anti-breast cancer : Curcumin
29
Busari ZA, Dauda KA1, Morenikeji OA, Afolayan F, Oyeyemi OT, Meena J, Sahu D, Panda AK(2017). Antiplasmodial Activity and Toxicological Assessment of Curcumin PLGA-Encapsulated Nanoparticles. Frontiers in Pharmacology. 8:622. DOI: 10.3389/fphar.2017.00622
Antimalarial : Curcumin
Antiplasmodial : Curcumin
30
Abbaoui A, Chatoui H, El Hiba O, Gamrani H(2017). Neuroprotective effect of curcumin-I in copper-induced dopaminergic neurotoxicity in rats: A possible link with Parkinson’s disease. Neuroscience Letters. 660:103-108. DOI: 10.1016/j.neulet.2017.09.032
Neuroprotective : Curcumin
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