Full Text                                                                            Full-Text Online        Genetic and molecular basis of nonhost disease resistance: complex, yes; silver bullet, no Current Opinion in Plant Biology ;  2012  [Vol.4]  Pages:- Abstract Nonhost resistance (NHR), in which a successful pathogen on some plants fails to overcome host barriers on others, has attracted much attention owing to its potential for robust crop improvement. Recent advances reveal that a multitude of underlying mechanisms contribute to NHR, ranging from components shared with recognition-based defenses up to recessive susceptibility factors involved in plant primary metabolism. Most NHR appears multi-factorial and quantitative. This implies that there is no single, ?silver bullet? NHR mechanism that can be used to broadly restrict pathogens in many or all crops. Keywords