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EST annotation of Radopholus similis

Domains present in R.similis and their functions

Insulin-like growth factor binding proteinsecreted proteins, which bind to IGF-I and IGF-II with high affinity and modulate the biological actions of IGFs.
Alpha-defensinexpressed primarily in leukocytes and epithelia.play an important role in the innate and adaptive immune response
2Fe-2S ferredoxin, iron-sulphur binding siteelectron carrier proteins with an iron-sulphur cofactor that act in a wide variety of metabolic reactions, iron binding and oxidoreductase activity
von Willebrand factoradhesive protein that plays a key role in platelet function by mediating the initiation and progression of thrombus formation atsites of vascular injury
Antifreeze protein, type Iprevent organism from freezing under very cool environment
Thiolase, active siteinvolved in both degradative pathways and biosynthetic pathways
signal peptidessignal peptide domain
ferredoxin, iron-sulphur binding siteelectron carrier proteins found in metabolic enzymes
EGF-like region, conserved siteepidermal growth factor? calcium-binding, conserved site
Anaphylatoxin/fibulinlarge glycoproteins that have important functions in the immune response and host defence
Tubulin, conserved siteglobular protein that polymerize into microtubules
Integrin beta subunitinvolved in cell adhesion, migration, homing, pattern formation, and signal transduction
4Fe-4S ferredoxin, iron-sulphur bindingelectron transfer
Cystine knot, C-terminaladhesive protein
Expansin 45, endoglucanase-likeunusual proteins that mediate cell wall extension in plants
Janus-atracotoxinfamily of insecticidal neurotoxins Biological Process: pathogenesis (GO:0009405)
Potassium channel, voltage dependenttransmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane
Hydrophobin, conserved sitehydrophobic proteins are structural constituent of cell wall
Pollen allergen Poa pIX/Phl pVI, C-terminalBiological Process: type I hypersensitivity (GO:0016068) , hypersensitivity reactions of the immune system to specific substances called pollen allergens